Clemson is a significant favorite in its matchup with undefeated NC State in Week 5.

The Tigers opened as 6-point favorites in this game, according to CircaSports. The total has been set at 44.5.

Both Clemson and NC State enter this game with a 4-0 record. The winner will have a commanding advantage in the race for the ACC Atlantic crown, although Florida State, Syracuse and Wake Forest are still in the mix as well.

NC State won this game a year ago in Raleigh, so Clemson will be looking for revenge on Saturday. The Tigers won the previous 8 meetings in this series.

Clemson will also be the host of ESPN’s College GameDay for this top 25 matchup. Clemson is at No. 5 and NC State is ranked No. 10 this week.

The Tigers are coming off an overtime win over Wake Forest. NC State blew out UConn this week.

Kickoff is at 8:30 p.m. ET on Saturday night.